The medicinal use of plants as analgesic or antinociceptive drugs in traditional therapy is estimated. Bioactive aqueous extracts of twelve yucatecan plants. The traditional medicine refers to a broad range of ancient natural health care practices including folktribal practices as well as ayurveda, siddha, amchi and unani. The cardioprotective effect of medicinal plantsherbal products during cardiovascular ailments has been demonstrated by attenuating the damage in cardiac muscle cells, vascular smooth muscle cells vsmcs, endothelial cells ecs, and macrophages and monocytes. Antibacterial and anticancer activity of ethnomedicinal plants used. Herbal medicine practitioners recommend calmative herbs, which provide a soothing effect to the body. Achyranthes aspera is an important medicinal plant and all parts are used in medicines, seeds and roots are the most. Antinephrotoxic activity of some medicinal plants from. Cardioprotective potential of plant derived molecules.
Medicinal plants play a golden role not only as traditional medicine but also as trade commodities, meeting the demand of distant. An overview of medicinal plants for potential cardio. Two plants showed promising cardioprotective potential in the order calligonum comosum cordia myxa. In addition, inappropriate use wrong plant parts, dose, frequency, route of administration, preparation, etc. Cardioprotective activity of alcoholic extract of t.
Antibacterial and anticancer activity of ethnomedicinal plants used in the jongilanga. Review of medicinal plants for antiobesity activity abstract obesity is a complex health issue to address, it is a serious and chronic disease that can have a negativeeffect on many systems in your body. Reported cardioprotective activities of medicinal plants against cardiotoxicity. In the present scenario, obesity is the major public health problem with about 1. Antioxidant and antiinflammatory medicinal plants have. In both plant, the cardioprotective activity was attributed to the antioxidant activities associated with the presence of flavonoids and phenolics. Because of this, we turn our attention to medicinal plants as possible sources. Trees with hepatoprotective and cardioprotective activities. Pdf biomass production and antibacterial activity of.
Antioxidant, antihypertensive, antihyperglycemic, and. Virani institute of pharmacy and research centre, badhada, savarkundla, gujarat, india. This study led to the wealth knowledge of traditional medicinal plants that are being used as a diabetic treatment. Many medicinal plants have been found to possess beneficial effects conditions like cancer, liver diseases, cataract and myocardial ischemia 12. Cardioprotective and other beneficial effects of some. Cardioprotective and metabolomic profiling of selected. Antinephrotoxic activity of some medicinal plants from tribal rich pockets of odisha satyaranjan mishra, saumya ranjan pani, 1 and sabuj sahoo 2 k. Cardioprotective potential of plantderived molecules. Specifically we focus on four key plants which have been shown by scientific andor traditional in vitro studies to lower plasma cholesterol and lipid. The results revealed that the inhibition of neinduced vasocontraction is due to a decrease in calcium influx from the extracellular space, which enhanced by. Acid extracts of the plants were more effective than the aqueous or buffer extracts against alternaria spp. Cardioprotective effect of mangiferin on isoproterenol induced myocardial. Structure activity relationship sar a myriad of epidemiological studies have suggested a negative correlation between medicinal flavonoids consumption and development of various diseases,, thereinto, flavonoids with typical structures can interact with enzyme systems involved in crucial pathways, showing effective polypharmacological behaviors. Evaluation of the cytotoxic activity of extracts from medicinal plants used for the treatment of malaria in kagera and lindi regions, tanzania.
Antimicrobial activity of selected medicinal plants against. Antimalarial activity of medicinal plants used in traditional. The cardioprotective and cardiotoxic effects of medicinal plants are attributable to bioactive components with direct or indirect effect on the heart and blood vessels. Cardioprotective activity of alcoholic extract of tinospora cordifolia willd. Analgesic activity of some indian medicinal plants. The free radicals produced in response to o 2 and feso 4 caused the strand cleavage of pbr322 plasmid dna and resulted in dna band streaking figure 2. Cooper r, hertog mgl medicinal plants, plants based foods and. Some indian traditional medicinal plants w ith antioxidant. Antibacterial activity of medicinal plants against pathogens from. Request pdf an overview of medicinal plants for potential cardioprotective activity cardiovascular diseases are lifethreatening leading to death. Therefore, interest in the examination of plants as potential sources of new drugs is increasing.
Pdf siddha system of medicines is known for its herbal in origin. The use of herbal supplements has become increasingly popular in recent years. Overweight and obesity may increase the risk of many health problems, including diabetes, heart disease, osteoarthritisand certain cancers. Jain s, dephillips r 1991 medicinal plants of india. H9c2 standard curves were generated to test for assay linearity which was obtained from. Several medicinal plants have been reported with antiinflammatory activity. Pain is a global public health problem with a high impact on life quality and a huge economic implication, becoming one of the most important enemies in modern medicine. Toxic principles can be found in different parts of medicinal plants. To elucidate the possible positive correlation between the antioxidant and cardioprotective effects, we studied some medicinal plants in detail. Details of indian medicinal plants having cardioprotective, therapeutic and antioxidant properties are given in table 1 2352. Recently, numerous side effects of synthetic drugs have lead to using medicinal plants as a reliable source of new therapy. It is characterized by redness, swollen joints, joint pain, its stiffness and loss of joint function.
The plant extract exhibited strong antiimplantation and uterotropic activity inhibition was 100% at a dose level of 400 mgkg. Certain medicinal herbs have disinfectant property, which destroys disease causing germs. The in vivo bioassay was conducted on formalin mosaddek et al. Obesity is characterized by increase in adipose cell size which is determined by amount of fat accumulated in the cytoplasm of. Additionally some of these plant extracts also showed cardioprotective activities in animal and cellular models. The methanol, ethanol and aqueous extracts of seven medicinal plants were evaluated for activity against medically important bacteria such as staphylococcus. Medicinal plants also can be poisonous, affecting the entire spectrum of organ systems, with some plants containing several toxic principles that affect different systems. Chloroform, butanol, ethyl acetate and nhexane extracts of these plants were used for antimicrobial screening. Anopheles is a genera of mosquitoes that are responsible for the transmission of malaria worldwide that causes millions of deaths every year. Maps database construction maps database is constructed using ms access. Vectorborne diseases are spreading all across the world, which results in economic and social disturbances. Some indian traditional medicinal plants w ith antioxidant activity.
The effect of ethanolic stembark extract of mammea africana sabine on total cholesterol, triglyceride and lipoproteins levels was studied on normal rats. Some of the medicinal plants with antiulcer activity a. Miers in calcium chloride induced cardiac arrhythmia in rats. Cytotoxicity and antimicrobial activity of selected plant species. Cardiotoxicity and cardioprotective effects of african.
A considerable number of these plants and plant based products have been widely used 14. All the plants exhibited protection of plasmid dna. Phytochemical analysis of traditional medicinal plants and their antimicrobial activity. Many medicinal plant extracts with various extracting solvents used, have shown effective activity against both m. Phytochemical analysis of traditional medicinal plants and. An experience from north east india minakshi b, jharna d, chanbi devi e, nayan t, partha pk, kundal n.
The plant was reported to possess cardio protective effect as well as antihypertensive effect and the mechanism for this pharmacological efficacy is by inhibiting specific. They studied the cardioprotection by determining the activity of. Hypolipidaemic and cardioprotective activity of mammea africana. The further investigation on these medicinal plants may lead to the discovery of novel bioactive compounds in the pharmaceutical industry. Evaluation of cardioprotective effect of tinospora cordifolia against isoprenaline induced myocardial infarction in rats. The aim of the current study was to explore the potential protective effects of methanolic extracts of these seven saudi plants against doxinduced cardiotoxicity in rats. Biomass production and antibacterial activity of justicia gendarussa. Hence, the present study was designed to evaluate the cardioprotective activity of alcoholic extract of t. Singh 1, poonam singh 1 scientist, division of toxicology, csircentral drug research institute, luckno w, u.
Medicinal plants with cardiovascular effects part 2. Medicinal plants and their uses medicinal herbs home. Among these uses, medicinal plants play a central role, not only as traditional. The mic values of the extracts were determined ranging. Review of medicinal plants for antiobesity activity. Evaluation of estrogenic activity of plant extracts for the potential. Medicinal plants have curative properties due to the presence of various complexes chemical substances. Screening of antioxidants from medicinal plants for. Medicinal plants play a key role in the human health care.
Coadministration of various medicinal plants possessing nephroprotective activity along with different nephrotoxic agents may attenuate its toxicity. Due to the diversity of medicinal plants and herbal medicines, it is dif ficult for. About 80% of the world population rely on the use of traditional medicine which is predominantly based on plant materials 1. The cardioprotective effect of medicinal plants herbal products during cardiovascular ailments has been demonstrated by attenuating the damage in cardiac muscle cells, vascular smooth muscle cells vsmcs, endothelial cells ecs, and macrophages and monocytes. It is the use of plants for medicinal purposes, and the study of such uses. Hypolipidaemic and cardioprotective activity of mammea. Antifertility activity of medicinal plants sciencedirect.
Cardiotoxicity is a condition that occurs during therapy with several cytotoxic drugs and may be the dose limiting factor in the cancer therapy or imbalanced diet and lifestyle. Evaluation of the potential cardioprotective activity of. In case of the rest of the medicinal plants the 2008, serotonin and egg. To determine the cardioprotective effect of the medicinal plant extracts, ic50 of doxorubicin were evaluated in comparison with the antioxidant standards. Miers in calcium chlorideinduced cardiac arrhythmia in rats. The extract 3090 mg kg1 was orally administered to rats for 21 days after which they were sacrificed and blood taken for analysis. Phytochemicals serve as the reservoirs of pharmacophore which can be utilized as templates for developing safe and potential novel cardioprotective agents in combating doxinduced. Medicinal plants of the family lamiaceae in pain therapy. Cardioprotective effect of mangiferin on isoproterenol. Pdf evaluation of the cytotoxic activity of extracts.
Inflammation is a part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells or irritants. An experience from north east india j pharm res phytochemical analysis of traditional medicinal plants and their antimicrobial activity. The activity demonstrated on the heart by the same medicinal plant or a bioactive compound could be protective or toxic depending on the concentration employed. Ancient literature has prescribed various herbs for the cure of kidney disease. Increasing role of the who monographs on selected medicinal plants over the past two decades, there has been a tremendous increase in the use of herbal medicine.